A widely used synthetic PI3K inhibitor for studying PI3K/Akt signaling, autophagy and apoptosis.
Selleck LY294002 is a synthetic PI3K inhibitor targeting PI3Kα, PI3Kδ and PI3Kβ with reported IC50 values of 0.5, 0.57 and 0.97 μM, respectively. It is commonly used to inhibit PI3K/Akt signaling and investigate cell proliferation, apoptosis and autophagosome formation.
Brand: Selleck Chemicals
Catalog number: S1105
Primary targets: PI3Kα, PI3Kδ and PI3Kβ
Additional reported targets: CK2, DNA-PK and mTOR
Synonyms: SF 1101, NSC 697286
CAS number: 154447-36-6
Molecular weight: 307.34
Form: Powder
Official product link: LY294002 – S1105
