A highly selective GSK-3 inhibitor for Wnt signaling, stem-cell and organoid research.
CHIR-99021 is a potent and selective inhibitor of glycogen synthase kinase-3 alpha and beta. By inhibiting GSK-3 and activating downstream Wnt/β-catenin signaling, it is widely used for maintaining pluripotent stem cells, directing cellular differentiation and supporting organoid culture.
Manufacturer: APExBIO
Catalog number: A3011
CAS number: 252917-06-9
Targets: GSK-3α and GSK-3β
Reported activity: IC50 values of approximately 10 nM and 6.7 nM
Storage: Store at −20°C
Applications: Wnt signaling, iPSC culture, stem-cell maintenance, differentiation and organoid research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/gsk-3-inhibitor-xvi.html
Contact Biolterna for the required formulation, available pack size or related stem-cell culture compounds.
