A small-molecule IKK and NF-κB pathway inhibitor for inflammation and cell-signaling research.
APExBIO Bay 11-7821, commonly known as BAY 11-7082, is a small-molecule inhibitor used to study IKK/NF-κB signaling, inflammatory responses and programmed cell death. It inhibits TNFα-mediated phosphorylation of IκB-α and can also suppress inflammasome-related signaling.
Manufacturer: APExBIO Technology
Catalog number: A4210
CAS number: 19542-67-7
Molecular weight: 207.25
Target: IKK/NF-κB pathway
Reported activity: NF-κB IC₅₀ approximately 10 μM
Available sizes: 10 mg, 25 mg, 50 mg and 100 mg
Solubility: Soluble in DMSO; insoluble in water
Storage: −20°C
Applications: NF-κB signaling, inflammation, apoptosis, inflammasome and cancer research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/bay-11-7821.html
Contact Biolterna for current availability, bulk quantities or a functionally comparable NF-κB inhibitor.
