A highly selective Bcl-2 inhibitor for apoptosis and cancer-cell survival research.
Selleck Venetoclax, also known as ABT-199, is a selective Bcl-2 inhibitor with a reported Ki below 0.01 nM. It shows substantially lower activity against Bcl-xL and Bcl-w and is widely used to study mitochondrial apoptosis, cancer-cell survival and resistance mechanisms.
Brand: Selleck Chemicals
Catalog number: S8048
Primary target: Bcl-2
Reported activity: Ki below 0.01 nM
Synonyms: Venetoclax, ABT-199, GDC-0199
CAS number: 1257044-40-8
Official product link: ABT-199 (Venetoclax) – S8048
