A selective ROCK inhibitor commonly used to improve survival of dissociated stem cells.
APExBIO Y-27632 Dihydrochloride is a small-molecule inhibitor of ROCK1 and ROCK2. It is widely used in stem-cell and organoid culture to improve the survival of dissociated cells and is also suitable for studying cytoskeletal organization, cell adhesion, migration and cytokinesis.
Manufacturer: APExBIO Technology
Catalog number: A3008
CAS number: 129830-38-2
Targets: ROCK1 and ROCK2
Reported activity: ROCK1 Kᵢ approximately 140 nM; ROCK2 Kᵢ approximately 300 nM
Available sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and 500 mg
Available solution: 10 mM in 1 mL DMSO
Storage: −20°C
Applications: Stem-cell culture, organoid culture, cytoskeleton, migration and ROCK signaling research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/y-27632-dihydrochloride.html
Contact Biolterna for the required package size, solution format or an alternative ROCK inhibitor.
