A potent 20S proteasome inhibitor for studying protein degradation, NF-κB signaling and apoptosis.
Selleck Bortezomib is a potent 20S proteasome inhibitor with a reported Ki of 0.6 nM. It is widely used to investigate ubiquitin–proteasome-dependent protein degradation, NF-κB signaling, autophagy and apoptosis.
Brand: Selleck Chemicals
Catalog number: S1013
Primary target: 20S proteasome
Reported activity: Ki 0.6 nM
Molecular weight: 384.24
Product type: Proteasome inhibitor
Form: Powder
Official product link: Bortezomib – S1013 Selleck Chemicals
