A hydrochloride form of the selective GSK-3 inhibitor CHIR-99021 for stem-cell and Wnt-pathway research.
CHIR-99021 HCl is the hydrochloride form of CHIR-99021, a selective inhibitor of GSK-3α and GSK-3β. It is frequently incorporated into stem-cell and organoid culture protocols to modulate Wnt/β-catenin signaling, promote self-renewal or support controlled differentiation.
Manufacturer: APExBIO
Catalog number: A8396
CAS number: 1797989-42-4
Targets: GSK-3α and GSK-3β
Reported activity: IC50 values of approximately 10 nM and 6.7 nM
Available sizes: Evaluation sample, 10 mM in 1 mL DMSO, 5 mg, 10 mg, 25 mg and 100 mg
Storage: Store at −20°C
Applications: Stem-cell culture, organoids, Wnt signaling and cellular differentiation
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/chir-99021-ct99021-hcl.html
Contact Biolterna to confirm the required CHIR-99021 formulation, pack size and current availability.
