A PI3K inhibitor widely used to inhibit autophagy in cellular research models.
MCE 3-Methyladenine, commonly abbreviated as 3-MA, is a phosphoinositide 3-kinase inhibitor widely used in autophagy research.
Its inhibition of class III PI3K suppresses autophagosome formation under commonly used experimental conditions. Because its effects can vary with concentration, treatment duration and nutrient conditions, appropriate experimental controls should be included.
Manufacturer: MedChemExpress
Catalog number: HY-19312
Product name: 3-Methyladenine
Synonym: 3-MA
CAS number: 5142-23-4
Molecular formula: C₆H₇N₅
Molecular weight: 149.15 g/mol
Targets: PI3K, autophagy and mitophagy pathways
Form: Solid
Purity: Refer to the current lot-specific COA
Available sizes: Multiple pack sizes available
Applications: Autophagy inhibition, PI3K signaling, mitophagy and cell-death research
Research use only: Not for human or veterinary use
Original product link: MCE 3-Methyladenine product page
Contact Biolterna for current pack sizes, batch-specific COA, solubility data and storage requirements.
The official MCE datasheet confirms catalog HY-19312, CAS 5142-23-4 and its classification as a PI3K and autophagy-pathway compound.
