A GPX4 inhibitor and ferroptosis inducer used in lipid-peroxidation and regulated cell-death research.
TargetMol RSL3 is a covalent GPX4 inhibitor that induces ferroptosis by impairing cellular defenses against phospholipid peroxidation. It is frequently used alongside Erastin and Ferrostatin-1 to investigate GPX4-dependent ferroptosis pathways.
Brand: TargetMol
Catalog number: T3646
Product name: RSL3
Synonym: RSL3 1S
CAS number: 1219810-16-8
Primary target: GPX4
Product type: Ferroptosis inducer
Applications: GPX4 research, ferroptosis, lipid peroxidation and cancer-cell studies
Research use only: Not for human or diagnostic use
Original product link: TargetMol RSL3 T3646 TargetMol
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