A selective and reversible JNK1/2/3 inhibitor for MAPK pathway and stress-response research.
APExBIO SP 600125 is an ATP-competitive inhibitor of the JNK family of mitogen-activated protein kinases. It is commonly used to investigate JNK-mediated phosphorylation, cellular stress responses, inflammatory signaling, apoptosis and proliferation.
Manufacturer: APExBIO Technology
Catalog number: A4604
CAS number: 129-56-6
Targets: JNK1, JNK2 and JNK3
Reported IC₅₀ values: 40 nM for JNK1, 40 nM for JNK2 and 90 nM for JNK3
Available sizes: 10 mg, 50 mg, 100 mg, 200 mg and 500 mg
Product type: ATP-competitive kinase inhibitor
Storage: −20°C
Applications: MAPK/JNK signaling, inflammation, cellular stress, apoptosis and cancer research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/sp-600125.html
Contact Biolterna for current availability, larger package sizes or an alternative JNK inhibitor.
