A potent V-ATPase inhibitor commonly used to block lysosomal acidification and late-stage autophagy.
TargetMol Bafilomycin A1 is a macrolide V-ATPase inhibitor commonly used to prevent lysosomal acidification and autophagosome–lysosome fusion. It is an established research tool for evaluating autophagic flux, lysosomal function, apoptosis and intracellular vesicle acidification.
Brand: TargetMol
Catalog number: T6740
Product name: Bafilomycin A1
Synonym: Baf A1
CAS number: 88899-55-2
Primary target: Vacuolar-type H⁺-ATPase
Reported activity: IC50 approximately 0.44 nM
Product type: V-ATPase and late-stage autophagy inhibitor
Applications: Autophagic-flux assays, lysosomal research and apoptosis studies
Available formats: Solid compound and selected DMSO solution formats
Research use only: Not for human or diagnostic use
Original product link: TargetMol Bafilomycin A1 T6740 TargetMol
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