A selective CDK4 and CDK6 inhibitor for cell-cycle and cancer-signaling research.
Palbociclib, also known as PD 0332991, is a selective CDK4 and CDK6 inhibitor. MCE reports IC50 values of 11 nM for CDK4 and 16 nM for CDK6. It is commonly used to study retinoblastoma-protein signaling, G1 cell-cycle arrest, cellular senescence and resistance to CDK4/6 inhibition.
Manufacturer: MedChemExpress (MCE)
Catalog number: HY-50767
CAS number: 571190-30-2
Molecular formula: C24H29N7O2
Molecular weight: 447.53
Primary targets: CDK4 and CDK6
Research areas: Cell cycle, oncology and cellular senescence
Available sizes: Multiple pack sizes available
Purity: Refer to the current lot-specific COA
Research use only: Not for human or veterinary use
Original product link: MCE Palbociclib product page
Contact Biolterna for current availability, batch documentation or alternative CDK4/6 inhibitors.
