A selective EGFR tyrosine-kinase inhibitor for cancer signaling and drug-resistance research.
Gefitinib, also known as ZD1839, is a potent, selective and orally active EGFR tyrosine-kinase inhibitor. MCE reports an IC50 of 33 nM for EGFR. It is widely used to investigate EGFR signaling, cellular proliferation, apoptosis and mechanisms of sensitivity or resistance to targeted inhibitors.
Manufacturer: MedChemExpress (MCE)
Catalog number: HY-50895
CAS number: 184475-35-2
Molecular formula: C22H24ClFN4O3
Molecular weight: 446.90
Primary target: EGFR
Research areas: Cancer signaling, kinase inhibition and drug resistance
Available sizes: Multiple pack sizes available
Purity: Refer to the current lot-specific COA
Research use only: Not for human or veterinary use
Original product link: MCE Gefitinib product page
Contact Biolterna for current availability, lot-specific COA or other EGFR research inhibitors.
