A classic PI3K and autophagy inhibitor commonly used to block autophagosome formation.
Selleck 3-Methyladenine is a PI3K inhibitor targeting Vps34 and PI3Kγ with reported IC50 values of 25 and 60 μM in HeLa cells. It is widely used to inhibit autophagosome formation and investigate the role of class III PI3K in autophagy. Prepared solutions are unstable and should generally be used promptly.
Brand: Selleck Chemicals
Catalog number: S2767
Primary targets: Vps34 and PI3Kγ
Reported activity: IC50 25 μM and 60 μM
Synonyms: 3-MA, NSC 66389
CAS number: 5142-23-4
Molecular weight: 149.15
Official product link: 3-Methyladenine (3-MA) – S2767
