A classic p38 MAPK inhibitor used in inflammation, stress-response and cytokine-signaling research.
Selleck SB203580, also known as Adezmapimod, is a p38 MAPK inhibitor with reported cellular IC50 values of approximately 0.3–0.5 μM. It is commonly used to investigate inflammatory signaling, cytokine production, cellular stress responses and MAPK-dependent processes.
Brand: Selleck Chemicals
Catalog number: S1076
Primary target: p38 MAPK
Reported activity: IC50 0.3–0.5 μM in THP-1 cells
Synonyms: Adezmapimod, RWJ 64809
Molecular weight: 377.43
Official product link: SB203580 (Adezmapimod) – S1076
