A selective V-ATPase inhibitor for studying lysosomal acidification and autophagic flux.
Bafilomycin A1 is a selective and reversible inhibitor of vacuolar-type H⁺-ATPases. By preventing organelle acidification, it interferes with lysosomal degradation and autophagosome–lysosome function. It is widely used to evaluate autophagic flux and investigate lysosomal biology.
Manufacturer: APExBIO
Catalog number: A8627
CAS number: 88899-55-2
Target: Vacuolar-type H⁺-ATPase
Reported activity: IC50 approximately 4–400 nM, depending on the experimental system
Available sizes: 100 μg, 500 μg, 1 mg, 5 mg and 10 mg
Storage: Desiccate at −20°C
Applications: Autophagic-flux analysis, lysosomal biology and intracellular pH research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/bafilomycin-a1.html
Contact Biolterna for current pack-size availability or other autophagy-related research compounds.
