A potent irreversible PI3K inhibitor commonly used in PI3K signaling and autophagy research.
Selleck Wortmannin is a potent PI3K inhibitor with a reported IC50 of 3 nM in cell-free assays. It also inhibits DNA-PK and ATM and blocks autophagosome formation, making it useful for studying PI3K signaling, DNA-damage responses and autophagy.
Brand: Selleck Chemicals
Catalog number: S2758
Primary target: PI3K
Reported activity: IC50 3 nM
Additional reported targets: DNA-PK, ATM and PLK1
Synonym: SL-2052
CAS number: 19545-26-7
Molecular weight: 428.43
Official product link: Wortmannin – S2758
