A reversible, cell-permeable proteasome inhibitor used in ubiquitination, autophagy and apoptosis research.
TargetMol MG-132 is a cell-permeable peptide aldehyde that reversibly inhibits the 26S proteasome. It is frequently used to prevent proteasomal protein degradation and investigate ubiquitin-dependent pathways, autophagy, apoptosis and cellular stress responses.
Brand: TargetMol
Catalog number: T2154
Product name: MG-132
Synonyms: MG132, Z-Leu-Leu-Leu-CHO, Z-LLL-al
CAS number: 133407-82-6
Primary target: 26S proteasome
Reported activity: Approximately 100 nM against the 20S proteasome in cell-free testing
Product type: Small-molecule proteasome inhibitor
Applications: Proteasome inhibition, ubiquitination, autophagy and apoptosis research
Research use only: Not for human or diagnostic use
Original product link: TargetMol MG-132 T2154 TargetMol
Contact Biolterna for the required solid or DMSO solution format and current batch documents.
