A potent PARP1 and PARP2 inhibitor for DNA-damage and synthetic-lethality research.
Olaparib, also known as AZD2281 or KU0059436, is a potent, orally active inhibitor of PARP1 and PARP2. MCE reports IC50 values of 5 nM and 1 nM for PARP1 and PARP2, respectively. It is frequently used to investigate DNA-damage repair, replication stress, homologous recombination deficiency and synthetic lethality.
Manufacturer: MedChemExpress (MCE)
Catalog number: HY-10162
CAS number: 763113-22-0
Molecular formula: C24H23FN4O3
Molecular weight: 434.46
Primary targets: PARP1 and PARP2
Research areas: DNA repair, oncology and synthetic lethality
Available sizes: Multiple pack sizes available
Purity: Refer to the current lot-specific COA
Research use only: Not for human or veterinary use
Original product link: MCE Olaparib product page
Contact Biolterna for current availability, lot documentation or other PARP research inhibitors.
