A potent mTOR inhibitor widely used in autophagy, aging, immunology and cancer research.
MCE Rapamycin, also known as Sirolimus, is a potent and selective inhibitor of the mammalian target of rapamycin pathway. It binds FKBP12 and subsequently inhibits mTOR complex 1 signaling.
Rapamycin is widely used to induce autophagy and investigate cell growth, metabolism, protein synthesis, immune regulation and aging-related pathways. MCE reports an IC₅₀ value of approximately 0.1 nM for mTOR inhibition in HEK293 cells.
Manufacturer: MedChemExpress
Catalog number: HY-10219
Product name: Rapamycin
Synonyms: Sirolimus; AY-22989
CAS number: 53123-88-9
Molecular formula: C₅₁H₇₉NO₁₃
Molecular weight: 914.17 g/mol
Target: mTOR
Biological effect: mTOR inhibition and autophagy activation
Form: Solid
Purity: Refer to the current lot-specific COA
Available sizes: Multiple pack sizes available
Applications: Autophagy, aging, immunology, metabolism and cancer research
Research use only: Not for human or veterinary use
Original product link: MCE Rapamycin product page
Contact Biolterna for current pack sizes, availability, batch-specific COA, storage information or bulk requirements.
MCE identifies HY-10219 as Rapamycin and reports potent mTOR inhibitory activity.
