A potent EGFR inhibitor for studying receptor phosphorylation, cell proliferation and drug resistance.
Selleck Erlotinib is an EGFR inhibitor with a reported IC50 of 2 nM. It is used to investigate EGFR activation, downstream MAPK and PI3K/Akt signaling, cancer-cell proliferation and mechanisms of sensitivity or acquired resistance.
Brand: Selleck Chemicals
Catalog number: S7786
Primary target: EGFR
Reported activity: IC50 2 nM
Synonym: CP-358774
CAS number: 183321-74-6
Official product link: Erlotinib (CP-358774) – S7786