A cell-permeable pan-caspase inhibitor widely used to suppress caspase-dependent apoptosis.
MCE Z-VAD-FMK is an irreversible, cell-permeable pan-caspase inhibitor used to inhibit caspase-dependent apoptosis.
It prevents the processing and activation of multiple caspases and is commonly used to distinguish apoptosis from other regulated cell-death pathways. Its protective effect can vary according to the cell model and death stimulus, so appropriate pathway markers should be included.
Manufacturer: MedChemExpress
Catalog number: HY-16658B
Product name: Z-VAD-FMK
Synonym: Z-VAD(OH)-FMK
CAS number: 187389-52-2
Molecular formula: C₂₂H₃₀FN₃O₇
Molecular weight: 467.49 g/mol
Target: Caspases
Biological effect: Inhibition of caspase-dependent apoptosis
Form: Solid
Purity: Refer to the current lot-specific COA
Available sizes: Multiple pack sizes available
Applications: Apoptosis inhibition, caspase research and regulated cell-death pathway analysis
Research use only: Not for human or veterinary use
Original product link: MCE Z-VAD-FMK product page
Contact Biolterna for current pack sizes, batch-specific COA, storage information and related caspase inhibitors.
MCE identifies HY-16658B as Z-VAD-FMK, a pan-caspase and ICE-like protease inhibitor used to suppress apoptosis.
