An N-linked glycosylation inhibitor commonly used to induce endoplasmic-reticulum stress.
Tunicamycin is an antibiotic and inhibitor of UDP-N-acetylglucosamine transfer during the initial stage of N-linked glycoprotein synthesis. The resulting accumulation of improperly processed proteins induces endoplasmic-reticulum stress and activates the unfolded protein response.
Manufacturer: APExBIO
Catalog number: B7417
CAS number: 11089-65-9
Target: GlcNAc phosphotransferase and N-linked glycosylation
Available sizes: 1 mg, 5 mg and 10 mg
Storage: Store at −20°C
Applications: ER stress, unfolded protein response, glycosylation and inflammation research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/tunicamycin.html
Contact Biolterna for current availability or other compounds used to induce and study cellular stress responses.
