A cell-permeable AMPK and BMP-signaling inhibitor used in metabolism and differentiation studies.
Dorsomorphin, also known as Compound C, is a reversible ATP-competitive inhibitor of AMP-activated protein kinase. It can also inhibit BMP-mediated Smad1/5/8 signaling and is used in research involving cellular metabolism, stem-cell differentiation and BMP pathway regulation.
Manufacturer: APExBIO
Catalog number: B3252
CAS number: 866405-64-3
Targets: AMPK and BMP signaling
Reported activity: AMPK Ki approximately 109 nM
Available sizes: 5 mg, 10 mg and 50 mg
Storage: Store at −20°C
Applications: AMPK signaling, metabolism, BMP signaling and stem-cell differentiation
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/dorsomorphin.html
Contact Biolterna for current availability or alternative AMPK and BMP pathway inhibitors.