APExBIO IWP-2

APExBIO IWP-2 is a small-molecule inhibitor of Porcupine, an acyltransferase required for the processing and secretion of Wnt proteins. It is frequently used to suppress Wnt/β-catenin signaling in developmental biology, stem-cell differentiation, organoid and cancer-research models.

Manufacturer: APExBIO Technology
Catalog number: A3512
CAS number: 686770-61-6
Molecular weight: 466.6
Targets: PORCN and Wnt production
Reported activity: Wnt pathway IC₅₀ approximately 27 nM
Available sizes: 5 mg, 10 mg, 25 mg, 50 mg and 100 mg
Solubility: Soluble in DMF; insoluble in water and ethanol
Storage: −20°C
Applications: Wnt signaling, stem-cell differentiation, developmental biology and cancer research
Research use only: Not for diagnostic or therapeutic use
Original product link: https://www.apexbt.com/iwp-2.html

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