A highly selective MEK1/2 inhibitor for blocking the MAPK/ERK signaling pathway.
Selleck U0126-EtOH is a selective inhibitor of MEK1 and MEK2 with reported IC50 values of 0.07 and 0.06 μM, respectively. It is widely used to suppress ERK phosphorylation and investigate MAPK signaling, cell proliferation, differentiation, autophagy and mitophagy.
Brand: Selleck Chemicals
Catalog number: S1102
Primary targets: MEK1 and MEK2
Reported activity: IC50 0.07 μM and 0.06 μM
Product form: Ethanol solvate
Molecular weight: 426.56
Official product link: U0126-EtOH – S1102 Selleck Chemicals
