An ATP-competitive ROCK inhibitor widely used in stem-cell, organoid and cytoskeletal research.
Y-27632 dihydrochloride is an ATP-competitive inhibitor of Rho-associated protein kinases. MCE reports Ki values of 220 nM for ROCK1 and 300 nM for ROCK2. It is commonly used to improve survival after dissociation of pluripotent stem cells and organoids and to investigate ROCK-dependent cytoskeletal signaling.
Manufacturer: MedChemExpress (MCE)
Catalog number: HY-10583
CAS number: 129830-38-2
Molecular formula: C14H23Cl2N3O
Molecular weight: 320.26
Primary targets: ROCK1 and ROCK2
Research areas: Stem cells, organoids, cell survival and cytoskeletal signaling
Available sizes: Multiple pack sizes available
Purity: Refer to the current lot-specific COA
Research use only: Not for human or veterinary use
Original product link: MCE Y-27632 Dihydrochloride product page
Contact Biolterna for current availability, batch documents or alternative ROCK inhibitors.
