A selective NEDD8-activating enzyme inhibitor for ubiquitination and protein-degradation research.
Cayman Chemical MLN4924, also known as Pevonedistat, is a selective inhibitor of NEDD8-activating enzyme. It is used to investigate neddylation, cullin-RING ligase activity, protein turnover, apoptosis and cancer-cell signaling.
Manufacturer: Cayman Chemical
Item number: 15217
Alternative name: Pevonedistat
CAS number: 905579-51-3
Molecular formula: C21H25N5O4S
Molecular weight: 443.5
Purity: ≥98%
Formulation: Crystalline solid
Available sizes: 1 mg, 5 mg and 10 mg
Storage: −20°C
Shipping: Room temperature in the continental US; international conditions may vary
Research use only: Not for human or veterinary diagnostic or therapeutic use
Original product link: Cayman Chemical product page
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