A fluorescence assay for evaluating mitochondrial permeability transition pore opening in living cells.
The Mitochondrial Permeability Transition Pore Assay uses Calcein AM together with cobalt-ion quenching to evaluate MPTP opening. Cytoplasmic fluorescence is quenched while mitochondrial fluorescence remains, allowing changes associated with pore opening to be studied.
Brand: Abbkine Scientific
Catalog number: KTA4002
Kit components: Calcein AM, CoCl₂, ionomycin and assay buffer
Detection method: Green fluorescence
Compatible platforms: Flow cytometer and fluorescence microscope
Applications: MPTP opening, mitochondrial dysfunction and apoptosis research
Storage: −20°C for up to 12 months; protect from light
Shipping condition: Gel pack with blue ice
Research use only: Not for diagnostic procedures
Original product link: https://www.abbkine.com/product/mitochondrial-permeability-transition-pore-assay-kta4002/
Contact Biolterna for current availability or an alternative mitochondrial-function assay.
