About Vazyme

Vazyme develops enzymes, reagents, kits, and integrated solutions for molecular biology research and molecular diagnostics. Its product portfolio covers nucleic acid extraction, reverse transcription, PCR, cloning, next-generation sequencing, and gene expression analysis.

The company focuses on enzyme technology and reagent development. Vazyme products support academic laboratories, biotechnology companies, pharmaceutical research, agricultural genomics, clinical research, and diagnostic assay development.

PCR and DNA Amplification

Vazyme offers polymerases, master mixes, and supporting reagents for routine and demanding PCR applications. The range includes:

• Standard PCR master mixes
• High-fidelity DNA polymerases
• Hot-start DNA polymerases
• Long-range PCR reagents
• Direct PCR products
• Multiplex PCR master mixes
• GC-rich template amplification products
• PCR enhancers and related reagents

These products support genotyping, mutation analysis, molecular cloning, sequencing preparation, pathogen research, and routine DNA amplification.

High-fidelity polymerases are suitable for experiments that require accurate sequence replication. Hot-start formulations help improve reaction specificity and reduce nonspecific amplification.

Quantitative PCR and Gene Expression Analysis

Vazyme provides ChamQ real-time PCR products for quantitative gene expression and nucleic acid detection. Available solutions include dye-based qPCR master mixes, probe-based master mixes, multiplex qPCR reagents, and one-step RT-qPCR products.

These reagents support:

• Relative and absolute gene expression analysis
• Pathogen detection
• Copy number analysis
• Genotyping
• MicroRNA research
• Low-abundance target detection
• Multiplex nucleic acid analysis

Optimized master mixes simplify reaction preparation and help laboratories achieve consistent amplification across different templates and instruments.

Reverse Transcription and RNA Research

Vazyme HiScript products support the synthesis of complementary DNA from RNA templates. The portfolio includes reverse transcriptases, cDNA synthesis kits, one-step RT-PCR products, and reagents for quantitative reverse transcription PCR.

These products are used in transcriptomics, gene expression studies, RNA virus research, microRNA analysis, and molecular diagnostic assay development.

Vazyme also offers products for RNA extraction, genomic DNA removal, and RNA sample preparation. Together, these reagents provide a connected workflow from biological sample to amplification and analysis.

Molecular Cloning

Vazyme provides ClonExpress products for rapid DNA assembly and recombinant plasmid construction. Homologous recombination-based cloning enables researchers to insert one or more DNA fragments into linearized vectors without relying on conventional restriction and ligation workflows.

The molecular cloning portfolio also includes:

• DNA ligases
• Restriction-related reagents
• DNA end-repair products
• Mutagenesis kits
• Competent cells
• Plasmid preparation products
• Gel extraction and PCR purification kits
• DNA markers

These products support gene cloning, vector construction, protein expression, synthetic biology, and genome engineering research.

Nucleic Acid Extraction and Purification

Vazyme offers magnetic bead-based and column-based products for DNA and RNA extraction. Available solutions support blood, cells, tissues, microorganisms, plants, formalin-fixed samples, and other biological materials.

The extraction portfolio includes products for:

• Genomic DNA purification
• Total RNA extraction
• Viral nucleic acid extraction
• Cell-free DNA preparation
• PCR product purification
• DNA size selection
• Plasmid DNA preparation
• Automated sample processing

Purified nucleic acids can be used in PCR, qPCR, cloning, sequencing, and other downstream molecular biology applications.

Next-Generation Sequencing

Vazyme VAHTS products support next-generation sequencing library preparation and sample processing. The portfolio covers DNA sequencing, RNA sequencing, target enrichment, library amplification, adapter ligation, and library purification.

NGS solutions are available for applications such as:

• Whole-genome sequencing
• Whole-exome sequencing
• Targeted sequencing
• RNA sequencing
• Metagenomic sequencing
• Epigenetic research
• Cancer genomics
• Liquid biopsy research
• Molecular breeding
• Microbial genomics

Library preparation products help researchers convert DNA or RNA samples into sequencing-ready libraries for commonly used NGS platforms.

Protein Research and Cell Biology

Vazyme supplies reagents for protein expression, detection, and cellular research. The portfolio includes protein markers, protein purification products, immunoassay-related reagents, cell viability products, and supporting laboratory consumables.

These products can support recombinant protein research, Western blotting, cell proliferation studies, drug screening, and assay development.

Molecular Diagnostics and Applied Research

Vazyme enzyme and reagent technologies are used in molecular diagnostic development and applied testing. Products support nucleic acid detection workflows for infectious diseases, hereditary conditions, oncology research, and other clinical research applications.

The company also provides solutions for animal health, food safety, agricultural genomics, molecular breeding, and environmental testing.

Key Research Areas

Vazyme products are relevant to:

• Molecular biology
• Genomics and transcriptomics
• Cancer research
• Infectious disease research
• Gene expression analysis
• Molecular diagnostics
• Synthetic biology
• Drug discovery
• Microbiology
• Agricultural genomics
• Molecular breeding
• Next-generation sequencing
• Biomarker research
• Clinical and translational research